diff --git a/dev/disable-plugins.sh b/dev/disable-plugins.sh
new file mode 100755
index 0000000000000000000000000000000000000000..96ce47d2b42971f6e6fc6a21511fe6477d1a2222
--- /dev/null
+++ b/dev/disable-plugins.sh
@@ -0,0 +1,73 @@
+#!/usr/bin/env bash
+##########################################################################
+#                                                                        #
+#  This file is part of Frama-C.                                         #
+#                                                                        #
+#  Copyright (C) 2007-2022                                               #
+#    CEA (Commissariat à l'énergie atomique et aux énergies              #
+#         alternatives)                                                  #
+#                                                                        #
+#  you can redistribute it and/or modify it under the terms of the GNU   #
+#  Lesser General Public License as published by the Free Software       #
+#  Foundation, version 2.1.                                              #
+#                                                                        #
+#  It is distributed in the hope that it will be useful,                 #
+#  but WITHOUT ANY WARRANTY; without even the implied warranty of        #
+#  MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the         #
+#  GNU Lesser General Public License for more details.                   #
+#                                                                        #
+#  See the GNU Lesser General Public License version 2.1                 #
+#  for more details (enclosed in the file licenses/LGPLv2.1).            #
+#                                                                        #
+##########################################################################
+
+if [ ! -f VERSION ]; then
+  echo "This script is meant to be run from the root directory of Frama-C"
+  exit 2
+fi
+
+if [ $# == "0" ]; then
+  rm -f src/plugins/dune
+  echo "All plugin enabled"
+  echo "Make sure to clean the current directory before rebuilding"
+  exit 0
+fi
+
+PLUGINS=
+for PLUGIN in "$@" ; do
+  PLUGINS="$PLUGINS $PLUGIN"
+done
+
+cat > src/plugins/dune <<EOL
+;; File generated by ./dev/disable-plugins.sh <PLUGINS>
+(include_subdirs no)
+;; Disabled plugin list:
+(data_only_dirs ${PLUGINS})
+(rule
+ (alias "frama-c-configure")
+ (deps (universe))
+ (action (progn
+  (echo "Disabled plug-in(s):")
+EOL
+
+for PLUGIN in "$@" ; do
+  echo "  (echo \"- src/plugins/$PLUGIN\")" >> src/plugins/dune
+done
+
+cat >> src/plugins/dune <<EOL
+)))
+;; Test
+(alias (name ptests) (deps (alias ptests_config)))
+(rule
+ (alias "ptests_config")
+ (deps (universe))
+ (action (progn
+  (echo "Testing with disabled plug-in(s):")
+EOL
+for PLUGIN in "$@" ; do
+  echo "  (echo \"- src/plugins/$PLUGIN\")" >> src/plugins/dune
+done
+echo ")))" >> src/plugins/dune
+
+echo "Disabled plug-ins: $PLUGINS"
+echo "Make sure to clean the current directory before rebuilding"